|
KMID : 1143220190620040224
|
|
Obstetrics & Gynecology Science
2019 Volume.62 No. 4 p.224 ~ p.232
|
|
|
How much have the perinatal outcomes of triplet pregnancies improved over the last two decades?
|
|
Kyeong Kyu-Sang
Shim Jae-Yoon
Oh Soo-Young
Won Hye-Sung
Lee Pil-Ryang
Kim Ahm
Yun Sung-Cheol
Kang Pureun-Narae
Choi Suk-Joo
Roh Cheong-Rae
|
|
|
Abstract
|
|
|
Objective: This study was conducted to demonstrate the temporal trends in perinatal outcomes of triplet pregnancies over the last two decades.
Methods: The medical records of patients with triplet pregnancies at two Korean tertiary-care hospitals from 1992 to 2012 were retrospectively reviewed in regard to maternal and neonatal outcomes. The study was divided into two periods for analysis: period I (1992?2001) and period II (2003?2012).
Results: Over a 21-year period, 65 women with triplet pregnancies and 185 neonates were analyzed. Period II, when compared with period I, was associated with improved maternal outcomes, characterized by a decreased incidence of preeclampsia (31.8% vs. 2.3%, P=0.002) and anemia (68.2% vs. 30.2%, P=0.003) during pregnancy. Regarding neonatal aspects, the composite morbidity of period II was significantly decreased compared with that of period I, as assessed with a generalized estimating equation for logistic regression (26.2% vs. 8.1%, P=0.03). Multivariable analysis revealed that the gestational age at delivery and the period were significantly associated with the composite neonatal morbidity (P<0.001 and 0.007, respectively).
Conclusion: Improved neonatal morbidity was associated with a higher gestational age at delivery and with the more recent decade.
|
|
|
KEYWORD
|
|
|
Triplets, Pregnancy, Preterm birth, Pregnancy outcome
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
  
|